Cigarette smoking harms nearly every organ in the body and remains the leading preventable cause of premature death in the United States, contributing to an estimated 480,000 deaths annually. Smokers aged 60 and older face a twofold increase in mortality compared to nonsmokers, dying approximately six years earlier. While nicotine itself is not carcinogenic, tobacco smoke contains at least 69 cancer-causing chemicals, making smoking responsible for at least 30% of all cancer deaths. Overall cancer death rates are twice as high among smokers as nonsmokers, with heavy smokers having a fourfold greater risk. Quitting smoking yields immediate health benefits, and depending on the age of cessation, some or all of the reduced life expectancy can be regained.

Key Factors:

1. Cancer Risks:
   • Lung cancer: Smoking is linked to 80–90% of cases and 80% of deaths.
   • Other cancers: Mouth, pharynx, larynx, esophagus, stomach, pancreas, cervix, kidney, bladder, acute myeloid leukemia.
   • Smokeless tobacco: Associated with cancers of the pharynx, esophagus, stomach, lung, and colorectal cancer.
2. Lung Diseases:
   • Chronic bronchitis and emphysema.
   • Worsened asthma symptoms in adults and children.
   • Leading risk factor for chronic obstructive pulmonary disease (COPD), which is irreversible once developed.
3. Heart Disease:
   • Increases risk of stroke, heart attack, vascular disease, and aneurysm.
   • Responsible for 40% of smoking-related deaths.
   • Causes coronary heart disease, the leading cause of death in the U.S.
4. Other Health Conditions:
   • Rheumatoid arthritis, inflammation, impaired immune function.
   • Reduced health-related quality of life in young smokers aged 26–41.
   • Potential link to Type 2 Diabetes through pathways between the pancreas and brain.
5. Benefits of Quitting:
   • Lung damage repair over time (except in COPD).
   • Improved overall health and reduced risk of smoking-related diseases.

The devastating impact of smoking on nearly every aspect of health—causing cancers, lung diseases, heart conditions, and a host of other ailments—underscores the urgent need to quit. While the damage caused by smoking is significant, the good news is that quitting can lead to remarkable health benefits, including the repair of lung damage, improved quality of life, and a lower risk of life-threatening diseases. Whether you’re a long-term smoker or have recently started, it’s never too late to take the first step toward a healthier future. Seek support from loved ones, healthcare professionals, or smoking cessation programs to embark on this life-changing journey. Quitting smoking not only adds years to your life but also greatly improves the quality of those years—an investment in your well-being and the peace of mind of those who care about you.

**By prioritizing the health and safety of its young residents, Minnesota is investing in a brighter, healthier future for all.**

Reference: https://nida.nih.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/what-are-physical-health-consequences-tobacco-use